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1

Segmented linear modelling of CHO fed-batch culture and its application to large scale production

Yahia, Bassem Ben, Gourevitch, Boris, Malphettes, Laetitia, Heinzle, Elmar

Journal:

Biotechnology and Bioengineering

Year:

2016

Language:

english

File:

PDF, 2.05 MB

english, 2016

2

From Clone Selection to 80L Bioreactor Production: Better, Faster, Leaner

Clincke, Marie-Françoise, Delouvroy, Frédéric, Révérend, Guillaume L, Stofferis, Jimmy, Hinchliffe, Matthew, Malphettes, Laetitia

Journal:

BMC Proceedings

Year:

2015

Language:

english

File:

PDF, 298 KB

english, 2015

3

Medium and feed optimization for fed-batch production of a monoclonal antibody in CHO cells

Nadine Kochanowski, Gaetan Siriez, Sarah Roosens, Laetitia Malphettes

Journal:

BMC Proceedings

Year:

2011

Language:

english

File:

PDF, 241 KB

english, 2011

4

Feeding strategy optimization in interaction with target seeding density of a fed-batch process for monoclonal antibody production

Clincke, Marie-Françoise, Mathy, Grégory, Gimenez, Laura, Le Révérend, Guillaume, Fessler, Boris, Stofferis, Jimmy, Yahia, Bassem, Bonsu-Dartnall, Nicola, Malphettes, Laetitia

Journal:

BMC Proceedings

Year:

2013

Language:

english

File:

PDF, 348 KB

english, 2013

5

Technology transfer and scale down model development strategy for biotherapeutics produced in mammalian cells

Kochanowski, Nadine, Malphettes, Laetitia

Journal:

BMC Proceedings

Year:

2013

Language:

english

File:

PDF, 619 KB

english, 2013

6

Scale-up considerations for monoclonal antibody production process: an oxygen transfer flux approach

Gimenez, Laura, Simonet, Claire, Malphettes, Laetitia

Journal:

BMC Proceedings

Year:

2013

Language:

english

File:

PDF, 565 KB

english, 2013

7

Evaluation of the advanced micro-scale bioreactor (ambr™) as a highthroughput tool for cell culture process development

Delouvroy, Frédéric, Le Reverend, Guillaume, Fessler, Boris, Mathy, Gregory, Harmsen, Mareike, Kochanowski, Nadine, Malphettes, Laetitia

Journal:

BMC Proceedings

Year:

2013

Language:

english

File:

PDF, 137 KB

english, 2013

8

Macroscopic modeling of mammalian cell growth and metabolism

Ben Yahia, Bassem, Malphettes, Laetitia, Heinzle, Elmar

Journal:

Applied Microbiology and Biotechnology

Year:

2015

Language:

english

File:

PDF, 584 KB

english, 2015

9

Genetic screening of male patients with primary hypogammaglobulinemia can guide diagnosis and clinical management

Vince, Nicolas, Mouillot, Gaël, Malphettes, Marion, Limou, Sophie, Boutboul, David, Guignet, Angélique, Bertrand, Véronique, Pellet, Philippe, Gourraud, Pierre-Antoine, Debré, Patrice, Oksenhendler, E

Journal:

Human Immunology

Year:

2018

Language:

english

File:

PDF, 1015 KB

english, 2018

10

Light Chain Deposition Disease with Bullous Skin Lesions Mimicking Atypical Bullous Pemphigoid

Malphettes, M, Bonnet, P, Schneider, P, Vignon, M, Baron, M, Bouaziz, J, Battistella, M

Journal:

Acta Dermato Venereologica

Year:

2018

Language:

english

File:

PDF, 2.14 MB

english, 2018

11

Etudes entreprises sur Cryptococcus fagi Baersp. en Haute-Normandie

MALPHETTES, C. B., Courtin, Claudine, Augustin, Sylvie

Journal:

Annales des Sciences Forestières

Year:

1980

File:

PDF, 293 KB

1980

12

Macrolide- and tetracycline-adjustable siRNA-mediated gene silencing in mammalian cells using polymerase II-dependent promoter derivatives

Laetitia Malphettes, Martin Fussenegger

Journal:

Biotechnology and Bioengineering

Year:

2004

Language:

english

File:

PDF, 396 KB

english, 2004

13

Highly efficient deletion of FUT8 in CHO cell lines using zinc-finger nucleases yields cells that produce completely nonfucosylated antibodies

Laetitia Malphettes, Yevgeniy Freyvert, Jennifer Chang, Pei-Qi Liu, Edmond Chan, Jeffrey C. Miller, Zhe Zhou, Thu Nguyen, Christina Tsai, Andrew W. Snowden, Trevor N. Collingwood, Philip D. Gregory, G

Journal:

Biotechnology and Bioengineering

Year:

2010

Language:

english

File:

PDF, 1.70 MB

english, 2010

14

Engineered Streptomyces quorum-sensing components enable inducible siRNA-mediated translation control in mammalian cells and adjustable transcription control in mice

Wilfried Weber, Laetitia Malphettes, Maria de Jesus, Ronald Schoenmakers, Marie Daoud El-Baba, Manuela Spielmann, Bettina Keller, Cornelia C. Weber, Petra van de Wetering, Dominique Aubel, Florian M.

Journal:

The Journal of Gene Medicine

Year:

2005

Language:

english

File:

PDF, 165 KB

english, 2005

15

6-hydroxy-nicotine-inducible multilevel transgene control in mammalian cells

Laetitia Malphettes, Ronald G. Schoenmakers, Martin Fussenegger

Journal:

Metabolic Engineering

Year:

2006

Language:

english

File:

PDF, 238 KB

english, 2006

16

Impact of RNA interference on gene networks

Laetitia Malphettes, Martin Fussenegger

Journal:

Metabolic Engineering

Year:

2006

Language:

english

File:

PDF, 311 KB

english, 2006

17

Development and fine-tuning of a scale down model for process characterization studies of a monoclonal antibody upstream production process

Mareike Harmsen, Jimmy Stofferis, Laetitia Malphettes

Journal:

BMC Proceedings

Year:

2011

Language:

english

File:

PDF, 75 KB

english, 2011

18

Studies of T cell reconstitution after hematopoietic stem cell transplant

B. Autran, M. Malphettes, N. Dhédin, G. Gorochov, V. Leblond, P. Debré

Journal:

Hematology and Cell Therapy

Year:

1997

Language:

english

File:

PDF, 144 KB

english, 1997

19

Immunoglobulin Dosage and Switch from Intravenous to Subcutaneous Immunoglobulin Replacement Therapy in Patients with Primary Hypogammaglobulinemia: Decreasing Dosage Does Not Alter Serum IgG Levels

Sylvain Thépot, Marion Malphettes, Anaëlle Gardeur, Lionel Galicier, Bouchra Asli, Lionel Karlin, Laurence Gérard, Richard Laumont, Marie-Laure Doize, Bertrand Arnulf, Claire Fieschi, Djaouïda Bengouf

Journal:

Journal of Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 175 KB

english, 2010

20

Parental Consanguinity is Associated with a Severe Phenotype in Common Variable Immunodeficiency

Claire Rivoisy, Laurence Gérard, David Boutboul, Marion Malphettes, Claire Fieschi, Isabelle Durieu, François Tron, Agathe Masseau, Pierre Bordigoni, Laurent Alric, Julien Haroche, Cyrille Hoarau, Ali

Journal:

Journal of Clinical Immunology

Year:

2012

Language:

english

File:

PDF, 206 KB

english, 2012

21

Detection and follow-up of fibroblast growth factor receptor 3 expression on bone marrow and circulating plasma cells by flow cytometry in patients with t(4;14) multiple myeloma

M. O. Chandesris, J. Soulier, S. Labaume, A. Crinquette, L. Repellini, K. Chemin, M. Malphettes, C. Fieschi, B. Asli, Y. Uzunhan, J. P. Fermand, J. C. Bories, B. Arnulf

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 616 KB

english, 2007

22

Dépérissement du hêtre en Haute-Normandie

C. B. Malphettes

Journal:

Forest Pathology

Year:

1974

File:

PDF, 1.11 MB

1974

23

Quorum-Sensing-Based Toolbox for Regulatable Transgene and siRNA Expression in Mammalian Cells

Wilfried Weber, Laetitia Malphettes, Matthias Rinderknecht, Ronald G. Schoenmakers, Manuela Spielmann, Bettina Keller, Petra Van de Wetering, Cornelia C. Weber, Martin Fussenegger

Journal:

Biotechnology Progress

Year:

2005

Language:

english

File:

PDF, 171 KB

english, 2005

24

Untersuchung über die Sexualentwicklung der mit Kairomonenfallen gefangenen Weibchen des Großen Braunen Rüsselkäfers

C. B. Malphettes, D. Fourgeres, F. X. Saintonge

Journal:

Journal of Pest Science

Year:

1994

File:

PDF, 1.58 MB

1994

25

Infection de colle biologique : une complication fatale d'une hypertension portale associée à un déficit immunitaire commun variable

O. Lidove, A. Gervais, M. Malphettes, A. Sauvanet, J.-L. Moretti, T. Papo

Journal:

La Revue de Médecine Interne

Year:

2007

Language:

french

File:

PDF, 66 KB

french, 2007

26

Maladie granulomateuse au cours du déficit immunitaire commun variable

M. Malphettes, E. Oksenhendler, L. Galicier, C. Fieschi

Journal:

La Revue de Médecine Interne

Year:

2008

File:

PDF, 118 KB

2008

27

Phénotype lymphocytaire T chez 252 patients avec déficit immunitaire commun variable

S. Georgin-Lavialle, C. Rabian, M. Malphettes, M. Carmagnat, J.-F. Viallard, M. Gardembas, R. Jaussaud, J.-L. Pasquali, E. Oksenhendler, L. Gérard, C. Fieschi

Journal:

La Revue de Médecine Interne

Year:

2008

Language:

french

File:

PDF, 52 KB

french, 2008

28

Étude de 83 patients ayant une splénomégalie au cours du déficit immunitaire commun variable

S. Georgin-Lavialle, L. Gérard, M. Malphettes, L. Galicier, J.-P. Fermand, V. Meignin, E. Oksenhendler, C. Fieschi

Journal:

La Revue de Médecine Interne

Year:

2008

Language:

french

File:

PDF, 67 KB

french, 2008

29

Hypogammaglobulinémies primitives découvertes à l’âge adulte

Claire Fieschi, Marion Malphettes, Lionel Galicier, Éric Oksenhendler

Journal:

La Presse Médicale

Year:

2006

Language:

french

File:

PDF, 345 KB

french, 2006

30

Comparison of sequential cytomegalovirus isolates in a patient with lymphoma and failing antiviral therapy

Alexandra Ducancelle, Stéphanie Belloc, Sophie Alain, Catherine Scieux, Marion Malphettes, Françoise Petit, Jean-Claude Brouet, Marie-José Sanson Le Pors, Marie-Christine Mazeron

Journal:

Journal of Clinical Virology

Year:

2004

Language:

english

File:

PDF, 188 KB

english, 2004

31

Manifestations cutanées révélant une cryofibrinogénémie associée à une gammapathie monoclonale

Delyon, J., Bezier, M., Cordoliani, F., Malphettes, M., Szalat, R., Bagot, M., Rybojad, M.

Journal:

Annales de Dermatologie et de Vénéréologie

Year:

2013

File:

PDF, 749 KB

2013

32

Improved transgene expression fine-tuning in mammalian cells using a novel transcription–translation network

Laetitia Malphettes, Martin Fussenegger

Journal:

Journal of Biotechnology

Year:

2006

Language:

english

File:

PDF, 503 KB

english, 2006

33

Defects in the CD19 complex predispose to glomerulonephritis, as well as IgG1 subclass deficiency

Vince, Nicolas, Boutboul, David, Mouillot, Gael, Just, Nicolas, Peralta, Maria, Casanova, Jean-Laurent, Conley, Mary Ellen, Bories, Jean-Christophe, Oksenhendler, Eric, Malphettes, Marion

Journal:

Journal of Allergy and Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 620 KB

english, 2011

34

Efficiency of immunoglobulin G replacement therapy in common variable immunodeficiency: correlations with clinical phenotype and polymorphism of the neonatal Fc receptor

Gouilleux-Gruart, V., Chapel, H., Chevret, S., Lucas, M., Malphettes, M., Fieschi, C., Patel, S., Boutboul, D., Marson, M.-N., Gérard, L., Lee, M., Watier, H., Oksenhendler, E.

Journal:

Clinical & Experimental Immunology

Year:

2013

Language:

english

File:

PDF, 310 KB

english, 2013

35

Clinical experience of bendamustine in relapsed or refractory Hodgkin lymphoma: a retrospective analysis of the French compassionate use program in 28 patients

Ghesquières, Hervé, Stamatoullas, Aspasia, Casasnovas, Olivier, Morschhauser, Franck, Gyan, Emmanuel, Gabarre, Jean, Malphettes, Marion, Clément, Laurence, Ferlay, Céline, Brice, Pauline

Journal:

Leukemia and Lymphoma

Year:

2013

Language:

english

File:

PDF, 283 KB

english, 2013

36

Granulomatoses au cours des déficits immunitaires primitifs de l’adulte

Pavic, M., Pasquet, F., Fieschi, C., Malphettes, M., Sève, P.

Journal:

La Revue de Médecine Interne

Year:

2013

Language:

french

File:

PDF, 259 KB

french, 2013

37

Process development and optimization of fed-batch production processes for therapeutic proteins by CHO cells

Clincke, Marie-Françoise, Harmsen, Mareike, Malphettes, Laetitia

Journal:

BMC Proceedings

Year:

2013

Language:

english

File:

PDF, 511 KB

english, 2013

38

Premier cas de granulomes cutanés aseptiques au cours d’une granulomatose septique chronique traités avec succès par infliximab

Enescu-Florica, C.-E., Bezier, M., Malphettes, M., Feuillet, S., Lortholary, O., Bagot, M., Rybojad, M.

Journal:

Annales de Dermatologie et de Vénéréologie

Year:

2011

Language:

french

File:

PDF, 96 KB

french, 2011

39

Complications du traitement de la leucémie lymphoïde chronique par Campath-1H (alemtuzumab ou MabCampath®) et par flavopiridol

MALPHETTES, M, LEVY, V

Journal:

Year:

2006

Language:

french

File:

PDF, 189 KB

french, 2006

40

Étude rétrospective portant sur 59 patients atteints de myélome et traités par dialyse : effets du bortézomib sur la survie des patients et la survie rénale

Beaini, S., Levy, B., Viglietti, D., Métivier, F., Malphettes, M., Fermand, J.P., Peraldi, M.N.

Journal:

Néphrologie & Thérapeutique

Year:

2014

Language:

french

File:

PDF, 73 KB

french, 2014

41

Prevention of Infections During Primary Immunodeficiency

Aguilar, C., Malphettes, M., Donadieu, J., Chandesris, O., Coignard-Biehler, H., Catherinot, E., Pellier, I., Stephan, J.-L., Le Moing, V., Barlogis, V., Suarez, F., Gerart, S., Lanternier, F., Jaccar

Journal:

Clinical Infectious Diseases

Year:

2014

Language:

english

File:

PDF, 191 KB

english, 2014

42

Infections in 252 Patients with Common Variable Immunodeficiency

Oksenhendler, Eric, Gérard, Laurence, Fieschi, Claire, Malphettes, Marion, Mouillot, Gael, Jaussaud, Roland, Viallard, Jean‐François, Gardembas, Martine, Galicier, Lionel, Schleinitz, Nicolas, Suarez,

Journal:

Clinical Infectious Diseases

Year:

2008

Language:

english

File:

PDF, 298 KB

english, 2008

43

Late‐Onset Combined Immune Deficiency: A Subset of Common Variable Immunodeficiency with Severe T Cell Defect

Malphettes, Marion, Gérard, Laurence, Carmagnat, Maryvonnick, Mouillot, Gaël, Vince, Nicolas, Boutboul, David, Bérezné, Alice, Nove‐Josserand, Raphaële, Lemoing, Vincent, Tetu, Laurent, Viallard, Jean

Journal:

Clinical Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 305 KB

english, 2009

44

Brentuximab vedotin in heavily treated Hodgkin and anaplastic large-cell lymphoma, a single centre study on 45 patients

Monjanel, Hélène, Deville, Laure, Ram-Wolff, Caroline, Venon, Marie-Dominique, Franchi, Patricia, Benet, Claire, de Kerviler, Eric, Malphettes, Marion, Thieblemont, Catherine, Brice, Pauline

Journal:

British Journal of Haematology

Year:

2014

Language:

english

File:

PDF, 66 KB

english, 2014

45

System for controlling pressure by acoustic means

Malphettes, Jean

Journal:

The Journal of the Acoustical Society of America

Year:

1979

Language:

english

File:

PDF, 253 KB

english, 1979

46

Clinico-biological characteristics and treatment of type I monoclonal cryoglobulinaemia: a study of 64 cases

Harel, Stephanie, Mohr, Melanie, Jahn, Isabelle, Aucouturier, Francoise, Galicier, Lionel, Asli, Bouchra, Malphettes, Marion, Szalat, Raphael, Brouet, Jean-Claude, Lipsker, Dan, Fermand, Jean-Paul

Journal:

British Journal of Haematology

Year:

2015

Language:

english

File:

PDF, 352 KB

english, 2015

47

Results of a Randomized Trial of Chlorambucil Versus Fludarabine for Patients With Untreated Waldenstrom Macroglobulinemia, Marginal Zone Lymphoma, or Lymphoplasmacytic Lymphoma

Leblond, V., Johnson, S., Chevret, S., Copplestone, A., Rule, S., Tournilhac, O., Seymour, J. F., Patmore, R. D., Wright, D., Morel, P., Dilhuydy, M.-S., Willoughby, S., Dartigeas, C., Malphettes, M.,

Journal:

Journal of Clinical Oncology

Year:

2013

Language:

english

File:

PDF, 154 KB

english, 2013

48

A novel mammalian expression system derived from components coordinating nicotine degradation in arthrobacter nicotinovorans pAO1

Journal:

Nucleic Acids Research

Year:

2005

Language:

english

File:

PDF, 2.23 MB

english, 2005

49

Chronic Urticaria and Monoclonal IgM Gammopathy (Schnitzler Syndrome)

Asli, Bouchra, Bienvenu, Boris, Cordoliani, Florence, Brouet, Jean-Claude, Uzunhan, Yurdagul, Arnulf, Bertrand, Malphettes, Marion, Rybojad, Michel, Fermand, Jean-Paul

Journal:

Archives of Dermatology

Year:

2007

Language:

english

File:

PDF, 80 KB

english, 2007

50

Good Syndrome: An Adult-Onset Immunodeficiency Remarkable for Its High Incidence of Invasive Infections and Autoimmune Complications

Malphettes, Marion, Gérard, Laurence, Galicier, Lionel, Boutboul, David, Asli, Bouchra, Szalat, Raphael, Perlat, Antoinette, Masseau, Agathe, Schleinitz, Nicolas, Le Guenno, Guillaume, Viallard, Jean-

Journal:

Clinical Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 173 KB

english, 2015

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